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عضو گروه پژوهشي بیومواد
عضو هيات علمي پژوهشکده فناوری نانو و موادپیشرفته
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اطلاعات شخصي

Ph.D. in Inorganic Chemistry (September 2007-July 2011)

Ph.D. Thesis: “Mixed-ligand palladium(II) cationic and anionic complexes synthesis, characterization, cytotoxicity and rich DNA-binding studies”; Supervisor: Prof. Hassan Mansouri Torshizi Advisor: Prof. Ali Akbar Saboury

Ms.C. in Inorganic Chemistry (September 2004- August 2006)

Master Thesis: “Studies of thermodynamic and binding parameters in the interaction of mononuclear [Pd(bpy)(Ph-dtc)]NO3 and binuclear [(bpy)Pd(p-phen-bdtc)Pd(bpy)](NO3)2 complexes with DNA”; Supervisor: Prof. Hassan Mansouri Torshizi

BSc. in Pure Chemistry (September 1999-April 2004)

اطلاعات پژوهشي و فناوري

  1. Saeidifar, H. Mansouri-Torshizi, G. Rezaei Behbehani, A. Divsalar, A.A. Saboury, A thermodynamic study of new designed complex of ethylendiamine 8-hydroxyquinolinato palladium(II) chloride with calf thymus DNA, Bulletin Korean Chemical Society, 2009, 30, 1951.
  2. Mansouri-Torshizi, M. Saeidifar, A. Divsalar, A. A. Saboury, S. Shahraki, Interaction studies of a novel, water-soluble and anti-cancer palladim(II) complex with calf thymus DNA, Bulletin Korean Chemical Society, 2010, 31, 435.
  3. Mansouri-Torshizi, M. Saeidifar, A. Divsalar, A.A. Saboury, Interaction studies between a 1,10-phenanthroline adduct of palladium(II) dithiocarbamate anti-tumor complex and calf thymus DNA. A synthesis spectral and in-vitro study, Spectrochimica Acta A, 2010, 77, 312.
  4. Mansouri-Torshizi, M. Saeidifar, G.R. Rezaei-Behbehani, A. Divsalar, A.A. Saboury, DNA binding studies and cytotoxicity of ethylenediamine 8-hydroxyquinolinato palladium(II) chloride, Journal of the Chinese Chemical Society, 2010, 57, 1299.
  5. Mansouri-Torshizi, M. Saeidifar, A. Divsalar, A.A. Saboury, Binding studies of a novel anti-tumor palladium(II) complex to calf thymus DNA, Nucleotide, nucleoside and nucleic acids, 2011, 30, 1.
  6. Mansouri-Torshizi, M. Saeidifar, Z. Yekke Ghasemi, M. Khastan, A. Divsalar, A.A. Saboury, DNA binding studies and cytotoxicity of the novel 1,10-phenanthroline palladium(II) complexes of dithiocarbamate derivatives, Korean Chemical Society, 2011, 55, 70.
  7. Mansouri-Torshizi, M. Saeidifar, F. Khosravi, A. Divsalar, A.A. Saboury, F. Hassani, DNA binding and antitumor activity of α-diimineplatinum(II) and palladium(II) dithiocarbamate complexes, Bioinorganic Chemistry and Application, 2011, 2011, 1.
  8. Mansouri-Torshizi, M. Saeidifar, A. Divsalar, A.A. Saboury, Study on interaction of DNA from calf thymus with 1, 10-phenanthrolinehexyldithiocarbamatopalladium(II) nitrate as potential antitumor agent, Journal of the biomolecular Structure and Dynamics, 2011, 28, 805.
  9. Mansouri-Torshizi, M. Saeidifar, F. Khosravi, A. Divsalar, A.A. Saboury, Z. Yekke Ghasemi, DNA-binding and thermodynamic parameters, structure and cytotoxicity of newly designed platinum(II) and palladium(II) anti-tumor complexes, Bulletin Korean Chemical Society, 2011, 32, 947.
  10. Saeidifar, H. Mansouri-Torshizi, A. Divsalar, A.A. Saboury, Spectroscopic investigation on the binding of the antitumoral Pd(II) complex to human serum albumin, Chinese Chemical Society, 2013, 60, 133.
  11. Saeidifar, H. Mansouri-Torshizi, A. Divsalar, A.A. Saboury, Novel 2,2′-bipyridine palladium(II) complexes with glycine derivatives: synthesis, characterization, cytotoxic assays and DNA-binding studies, Journal of the Iranian Chemical Society, 2013, 10, 1001.
  12. Saeidifar, H. Mansouri-Torshizi, Y. Palizdar, A. Divsalar, A.A. Saboury, Synthesis, characterization, and cytotoxicity studies of a novel palladium(II) complex and evaluation of DNA-binding aspects, Nucleosides, Nucleotides Nucleic Acids, 2013, 32, 366.
  13. Saeidifar, H. Mansouri-Torshizi, Y. Palizdar, M. Eslami-Moghaddam, A. Divsalar, A.A. Saboury, Synthesis, characterization, cytotoxicity and DNA binding studies of a novel anionic organopalladium(II) complex, Journal of Acta Chimica Slovenica, 2014, 61, 126.
  14. Eslami Moghadam, M. Saeidifar, F. Rostami-Charati, D. Ajloo, M. Ghadamgahi, Molecular dynamic simulation and spectroscopic investigation of some cytotoxic palladium(II) complexes interaction with human serum albumin, Combinatorial Chemistry & High Throughput Screening, 2014, 17, 781.
  15. Saeidifar, H. Mansouri-Torshizi, A.A. Saboury, Biophysical study on the interaction between two palladium(II) complexes and human serum albumin by multispectroscopic methods, Journal of Luminescence, 2015, 167, 391.
  16. Saeidifar, H. Mansouri-Torshizi, Investigation of the interaction between human serum albumin and antitumor palladium(II) complex containing 1,10-phenanthroline and dithiocarbamate ligands, Nucleosides, Nucleotides and Nucleic Acids, 2015, 34, 16.
  17. Karami, Z. Shirani-Sarmazeh, M. Hosseini-Kharat, J. Lipkowski, M. Saeidifar, Synthesis, spectral characterization, crystal structure and in vitro DNA/protein binding studies of phosphorous ylide palladacyclic complexes containing azide group, Journal of Photochemistry and Photobiology B: Biology, 2015, 144, 11.

  1. Saeidifar, A. Khanlarkhani, M. Eslami-Moghaddam, H. Mansouri-Torshizi, A.A. Saboury, Investigation of the binding behavior between the s-heterocyclic aromatic palladium(II) complex and human serum albumin: spectroscopic approach, Polycyclic Aromatic Compounds, 2016, 36, 40.
  2. Koohshekan, A. Divsalar, M. Saeidifar, A.A. Saboury, B. Ghalandari, A. Gholamian, A. Seyedarabi, Protective effects of aspirin on the function of bovine liver catalase: A spectroscopy and molecular docking study, Journal of Molecular Liquids, 2016, 218, 8.
  3. Eslami Moghadam, M. Saeidifar, A. Divsalar, H. Mansouri-Torshizi, A.A. Saboury, H. Farhangian, M. Ghadamgahi, Rich spectroscopic and molecular dynamic studies on the interaction of cytotoxic Pt(II) and Pd(II) complexes of glycine derivatives with calf thymus DNA, 2016, 34, 206.
  4. Saeidifar, Z. Sohrabi Jam, S. Shahraki, A. Khanlarkhani, M. Javaheri, A. Divsalar, H. Mansouri-Torshizid, A.A. Saboury, Multi-spectroscopic and electrochemical approaches of the interaction between a new binuclear agent and DNA, Journal of Biomolecular Structure and Dynamics, 2017, 35, 2557.
  5. Shahraki, M. Saeidifar, F. Shiri, A. Heidari, Assessment of the Interaction Procedure Between Pt(IV) Prodrug [Pt(5,5ʹ-dmbpy)Cl4 and Human Serum Albumin. Combination of Spectroscopic and Molecular Modeling Technique, Journal of Biomolecular Structure and Dynamics, 2017, 35, 3098.
  6. Saeidifar, H. Mansouri‑Torshizi, A. A. Saboury, Insight into the binding evaluation of two antitumor Pd(II) complexes with human serum albumin, Journal of Iranian Chemical Society, 2017, 14,189.
  7. Gholamian, Adeleh Divsalar, M. Saeidifar, B. Ghalandari, A.A. Saboury, B. Koohshekan, Generation of reactive oxygen species via inhibition of liver catalaseby oxalli-palladium: A spectroscopic and docking study, Process Biochemistry, 2017, 52, 165.
  8. Sohrabijam, M. Saeidifar, A. Zamanian, Enhancement of magnetofection efficiency using chitosan coated superparamagnetic iron oxide nanoparticles and calf thymus DNA, Colloids and Surfaces B: Biointerfaces, 2017, 152, 169.
  9. Shahraki, F. Shiri, M. Saeidifar, Evaluation of in silico ADMET analysis and human serum albumin interactions of a new lanthanum(III) complex by spectroscopic and molecular modeling studies, Inorganica Chimica Acta, 2017, 463 80.
  10. Alasvand, M. Saeidifar, A.A. Saboury, M. Mozafari, Controllable synthesis and characterisation of palladium (II) anticancer complex-loaded colloidal gelatin nanoparticles as a novel sustained-release delivery system in cancer therapy, IET Nanobiotechnology, 2017, 11, 591.
  11. Shahraki, F. Shiri, M. Saeidifar, Synthesis, characterization, in silico ADMET prediction, and protein binding analysis of a novel zinc(II) Schiff-base complex: Application of multispectroscopic and computational techniques, Journal of Biomolecular Structure and Dynamics, 2017, 36, 1666.

  1. Saeidifar, H.R. Mirzaei, N. AhmadiNasab, H. Mansouri-Torshizi, Mononuclear Pd(II) complex as a new therapeutic agent: synthesis, characterization, biological activity, spectral and DNA binding approaches, Journal of Molecular Structure, 2017, 1148, 339.
  2. Hosseini-Kharat, K. Karami, M. Saeidifar, C. Rizzoli, R. Zahedi-Nasab, Z. Sohrabijam, T. Sharifi, A novel Pd(II) CNO pincer complex of MR (methyl red): synthesis, crystal structure, interaction with human serum albumin (HSA) in vitro and molecular docking, New Journal of Chemistry, 2017, 41, 9897.
  3. Namdarian, A. Zamanian, A. Asefnejad, M. Saeidifar, Preparation, characterization, and drug delivery behavior of dexamethasone-loaded olibanum microsphere, Biomedical Engineering: Applications, Basis and Communications, 2018, 30, 1850031.
  4. Rezaei, M. Saeidifar, M. Javaheri, P. Sangpour, Colloidal HSA-Graphene oxide nanosheets for sustained release of oxaliplatin: Preparation, release mechanism, cytotoxicity and electrochemical approaches, Colloids and Surfaces B: Biointerfaces, 2018, 171, 10.
  5. Namdarian, A. Zamanian, A. Asefnejad, M. Saeidifar, Evaluation of Freeze-Dry Chitosan-Gelatin Scaffolds with Olibanum Microspheres Containing Dexamethasone for Bone Tissue Engineering, Polymer (Korea), 2018, 42, 982.
  6. A. Hosseini, M. Eslami Moghadam, M. Saeidifar, A.A. Saboury, Biological effect and molecular docking of anticancer palladium and platinum complexes with morpholine dithiocarbamate on human serum albumin as a blood carrier protein, Canadian Journal of Physiology and Pharmacology, 2018, 96, 1276.
  7. Shahraki, M. Saeidifar, M. Gomroki, Probing the in vitro binding mechanism between human serum albumin and La2O2CO3 nanoparticles, IET Nanobiotechnology, 2018, 12, 298.
  8. Farazi, M.R. Vaezi, M.J. Molaei, M. Saeidifar, A.A Behnam-Ghader, Effect of pH and temperature on doxorubicin hydrochloride release from magnetite/graphene oxide nanocomposites, Materials Today: Proceedings, 2018, 5, 15726.
  9. Shahraki, A. Heydari, M. Saeidifar, M. Gomroki, Biophysical and computational comparison on the binding affinity of three important nutrients to β-lactoglobulin: folic acid, ascorbic acid and vitamin K3, Journal of Biomolecular Structure and Dynamics, 2018, 36(14), 3651.
  10. Shahraki, A. Heidari, H.R. Mirzaei, M. Saeidifar, N. Ahmadinasab, H. Mansouri-Torshizi, Synthesis, Characterization, Cytotoxicity, DNA Binding and Computational Studies of an Anionic Palladium(II) Complex Derived from 8-Hydroxyquinoline and 1,1-Cyclobutanedicarboxylicate, Journal of the Iranian Chemical Society, 2018, 15, 1207.
  11. Javaheri, M. Saeidifar, S. Banijamali, S. Ghashghaei, M. Rafiee, Synthesized bimetallic electrocatalyst for oxygen reduction reaction in polymer electrolyte fuel cells, Journal of Nanostructures, 2018, 8(3), 294.

  1. Hosseini-Kharat, D. Zargarian, A.M. Alizadeh, K. Karami, M. Saeidifar, S. Khalighfard, L. Dubrulle,M. Zakariazadeh,J.P. Cloutier, Z. Sohrabijam, In vitro and in vivo antiproliferative activity of organo-nickel SCS-pincer complexes on estrogen responsive MCF7 and MC4L2 breast cancer cells. Effects of amine fragment substitutions on BSA binding and cytotoxicity, Dalton Transactions, 2018, 47, 16944.
  2. Khoramian, M. Saeidifar, A. Zamanian, A.A. Saboury, Synthesis and characterization of biocompatible ferrofluid based on magnetite nanoparticles and its effect on immunoglobulin G as an immune protein, Journal of Molecular Liquids, 2019, 273, 326.
  3. Mansouri-Torshizi, S. Zareian-Jahromi, K. Abdi, M. Saeidifar, Nonionic but water soluble, [Glycine-Pd-Alanine] and [Glycine-Pd-Valine] complexes. Their synthesis, characterization, antitumor activitiesand rich DNA/HSA interaction studies, Journal of Biomolecular Structure and Dynamics, 2019, 37(13), 3566.
  4. Shahraki, M. Saeidifar, F. Shiri, A Heidari, Synthesis, Characterization, Cytotoxicity and Detailed HSA Interaction of New Zinc(II) Complexes Containing Dithiocarbamate and Heterocyclic N donor Ligands, Polycyclic Aromatic Compounds, 2019, 39(3), 220.
  5. Shahraki, H. Samareh Delarami, M. Saeidifar, Catalase inhibition by two Schiff base derivatives. Kinetics, thermodynamic and molecular docking studies, Journal of Molecular Liquids, 2019, 287, 111003.
  6. Ziaaddini, M. Saeidifar, M. Eslami-Moghadam, M. Saberi, M. Mozafari, Improvement of efficacy and decrement cytotoxicity of oxaliplatin anticancer drug using bovine serum albumin nanoparticles: synthesis, characterisation and release behavior, IET Nanobiotechnology, 2020, 14(1), 105.
  7. Shahraki, H. Samareh Delarami, M. Saeidifar, R. Nejat, Catalytic activity and structural changes of catalase in the presence of Levothyroxine and Isoxsuprine hydrochloride, International Journal of Biological Macromolecules, 2020, 152, 126.
  8. Shahraki, M. Saeidifar, H. Samareh Delarami H. Kazemzadeh, Molecular docking and inhibitory effects of a novel cytotoxic agent with bovine liver catalase, Journal of Molecular Structure, 2020, 1205, 127590.
  9. Aminzadeh, M. Saeidifar, H. Mansouri-Torshizi, Synthesis, characterization, DNA binding, cytotoxicity, and molecular docking approaches of Pd(II) complex with N,O- donor ligands as a novel potent anticancer agent, Journal of Molecular Structure, 2020, 1215, 128212.
  10. Gholami, A. Divsalar, R. Abbasalipourkabir, N. Ziamajidi, M. Saeidifar, The simultaneous carrier ability of natural antioxidant of astaxanthin and chemotherapeutic drug of 5-fluorouracil by whey protein of βlactoglobulin: Spectroscopic and molecular docking study, Journal of Biomolecular Structure and Dynamics, 2020, accepted.
  11. Fattahian Kalhor, M. Saeidifar, H. Ramshini, A.A. Saboury, Interaction, cytotoxicity and sustained release assessment of a novel anti-tumor agent using bovine serum albumin nanocarrier, Journal of Biomolecular Structure and Dynamics, 2020, 38, 2546.
  12. Saeidifar, R. Sabbaghzadeh, N. Ahmadinasab, Biophysical Investigation and Antitumor Potential of Heterocyclic Palladium-Based Agent: Cytotoxicity, Spectroscopic and Molecular Docking Approaches in Interaction with Human Serum Albumin, Polycyclic Aromatic Compounds, 2020, accepted.
  13. Shahlaei, M. Saeidifar, A. Zamanian, Increasing the Effectiveness of Oxaliplatin using Colloidal Immunoglobulin G Nanoparticles: Synthesis, Cytotoxicity, Interaction, and Release Studies, Colloids and Surfaces B: Biointerfaces, 2020, 195, 111255.
  14. Saeidifar, R. Sabbaghzadeh, H. Mansouri Torshizi, A.A. Saboury, Binding evaluation of human serum albumin and a Pd(II) bischelate complex bearing N,O- alanine and O,O-malonate ligands: synthesis, characterization, biological investigation and molecular docking, Journal of the Iranian chemical society, 2020, accepted.
  15. Heidari, M. Ghassemzadeh, D. Fenske, O. Fuhr, M. Saeidifar, F. Mohsenzadeh, Unprecedented palladium(II) complex containing dipodal 1,3,4-thiadiazole derivatives: synthesis, structure, and biological and thermal investigations, New Journal of Chemistry, 2020, 44, 16769.

اطلاعات آموزشي

  1. Masoumeh Nozari (Nanotechnology, 2012); MERC

Development and electrochemically investigation of self-coloring nano structured coatings on anodized aluminium using Cu, Co and Ni Salts

  1. Zahra Sohrabijam (Nanotechnology, 2014); MERC

Synthesis, characterization and interaction between iron oxide nanoparticles (Fe3O4 and γ–Fe2O3) and ct-DNA as Gene delivery

  1. Neda Alasvand (Biomaterials, 2016); MERC

Synthesis and characterization of multilayered-gelatin nanoparticles intened for the sustained release of antitumor palladium(II) agent and its interaction with human serum albumin

  1. Farnaz Rezaei (Nanotechnology, 2016); MERC

Synthesis, characterization and drug release performance of graphen oxide-protein nanocomposite

  1. Shabnam Khoramian (Nanotechnology, 2016); MERC

The adsorption of human gamma globulins to magnetic iron oxide nanoparticles: A thermodynamic and binding study

  1. Nassim Fattahian Kalhor (Nanotechnology, 2018); MERC

Albumin – Curcumin derivative nanoparticles as a potential drug delivery system with biophysical properties

  1. Jaber Khodadi (Biomaterials, 2018); MERC

Design, Synthesis and Characterization of a Novel BSA/Graphen Oxide Drug Delivery System for Cancer Treatment

  1. Vahid Ziaaldini (Nanotechnology, 2018); MERC

Synthesis and identification of serum albumin nanoparticles for sustained release of anticancer drug

  1. Muna Shahlaei (Biomaterials, 2018); MERC

Design and synthesis of biocompatible drug release system for anti-cancer drug based on immunoglobulin antibody

  1. Yeganeh Karimi (Biomaterials, 2019); MERC

Targetable folate functionalized gammagluboline nanoparticles for sustained release of anticancer drug

  1. Maryam Oraki (Biomaterials, Current); MERC

Sustained release of 5-Flurouracil anticaner drug from a DNA-exosome nanocomposite as an intelligent drug delivery system, MERC

  1. Malak Nematian (Biomaterials, Current); MERC

Immobilization of BSA-5-fluorouracil nanoparticles in cellulose aerogels as a transdermal drug delivery system

  1. Golzar Ragheb (Biomaterials, Current); MERC and Iran University of Science and Technology

Synthesis and characterization of Hydroxyapatite-Albumin nanocarrier for delivering of Piroxicame as an anti-inflammatory drug: drug release study and its mechanism

  1. Ghazaleh Rahimi (Biomaterials, Current); MERC

Synthesis and characterization of albumin-exosome for sustained release of 5-flurouracil as an anticancer drug

اطلاعات تماس
تلفن : 36280040-26-98 داخلي 438
فکس : 36201888-26-98
آدرس : کرج - مشکين دشت - بلوار امام خميني - پژوهشگاه مواد و انرژی - پژوهشکده فناوری نانو و موادپیشرفته
ايميل : saeidifar@merc.ac.ir
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