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عضو هیات علمی پژوهشکده فناوری نانو و مواد پیشرفته
عضو گروه پژوهشی بیومواد
مرتبه علمی : دانشیار
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اطلاعات شخصی

کارشناسی ارشد ( رشته تحصیلی: مهندسی پزشکی-بیومتریال، سال اخذ مدرک:  1387، محل اخذ مدرک: دانشگاه صنعتی امیرکبیر)

دکتری ( رشته تحصیلی: مهندسی پزشکی-بیومتریال، سال اخذ مدرک:  1391، محل اخذ مدرک: دانشگاه صنعتی امیرکبیر)

اطلاعات پژوهشی و فناوری

  1. Mehrnaz Yadini, Maryam Saeidifar, Nader Nezafati, Seyed Mojtaba Daghighi, “Improvement of drug release and its efficacy in cancer treatment with advanced encapsulation methods in a novel hydrophobic agent into human serum albumin nanoparticles”, Results in Chemistry 14 (2025) 102156.
  2. Mohammad Reza Shafiei, Nader Nezafati, Saeed Karbasi, Anousheh Zargar Kharazi, “Rifampin-loaded Mesoporous Silica Nanoparticles Improved Physical and Mechanical Properties and Biological Response of Acrylic Bone Cement”, Journal of Medical Signals & Sensors 15(3) (2025) 1-9.
  3. Saeed Hesaraki, Nader Nezafati*, Mostafa Shahrezaee, “Effect of citric acid as a porogenic agent for fabrication of macroporous biphasic calcium phosphate scaffolds”, Current Materials Science, 18 (2025) 393-403.
  4. Mehdi Shams, Nader Nezafati*, Saeed Hesaraki, Mahmoud Azami, “Gelatin-containing functionally graded calcium sulfate/bioactive glass bone tissue engineering scaffold”, Ceramics International 50 (2024) 31700–31717.
  5. Saeed Hesaraki, Golshan Saba, Mostafa Shahrezaee, Nader Nezafati, Ziba Orshesh, Fahimeh Roshanfar, Shokoufeh Borhan, Birgit Glasmacher, Pooyan Makvandi, Yi Xu, “Reinforcing β-Tricalcium Phosphate Scaffolds: Impact of Functionalized Multi-Walled Carbon Nanotubes on Rheology and Performance for Potential Applications in.Bone Tissue Engineering”, Scientific Reports 14 (2024) 19055.
  6. Saeed Hesaraki, Mohammad Hassan Barounian, Shokoufeh Borhan, Mostafa Shahrezayee, Nader Nezafati, “Controlled release of a non-steroidal anti-inflammatory drug from a photocurable polymeric Calcium phosphate cement”, Journal of Biomaterials Science, Polymer Edition 34 (2023) DOI: 10.1080/09205063.2023.2193495 ).
  7. Efaf Beman, Shokoufeh Borhan, Saeed Hesaraki, Nader Nezafati*, “Macroporous Nanostructured Calcium Phosphate/Chitosan-Gelatin Composite Bone Tissue Engineering Scaffold”, Current Materials Science 16 (2023) 443-452 .

8.      Yeganeh Moayedee, Iman Mobasherpour, Sara Banijamali, Mansour Razavi, Nader Nezafati, “Effect of the nano-fluorapatite ceramic particles on mechanical behavior of fluoride varnishes”, Materials Chemistry and Physics 288 (2022) 126421.

9. Atefeh Derakhshani, Saeed Hesaraki, Nader Nezafati, Mahmoud Azami, “Wound closure, angiogenesis and antibacterial behaviors of tetracalcium phosphate/hydroxyethyl cellulose/hyaluronic acid/gelatin composite dermal scaffolds”, Journal of Biomaterials Science, Polymer 33 (2022) 605–626.

10. Mohammad Nouri-Felekori, Nader Nezafati*, Marzie Moraveji, Saeed Hesaraki, Tayebe Ramezani, “Bioorthogonal hydroxyethyl cellulose-based scaffold crosslinked via click chemistry for cartilage tissue engineering applications”, International Journal of Biological Macromolecules, 183 (2021) 2030-2043.

11. Saeed Hesaraki, Mohammad Nouri-Felekori, Nader Nezafati, Shokoufeh Borhan, “Preparation, characterization, and in vitro biological performance of novel porous GPTMS-coupled tragacanth/nano-bioactive glass bone tissue scaffolds”, Materials Today Communications 27 (2021) 102335.

12. Mojdeh Azizi, Mahdi Kalantar, Nader Nezafati, Ali Zamanian “Fabrication, characterization, and in vitro bioactivity evaluation of freeze-cast highly porous hardystonite ceramic reinforced by graphene oxide as a novel bone scaffold”, Journal of the Australian Ceramic Society (2021) https://doi.org/10.1007/s41779-021-00601-5.

13. Katayon Hemmati, Navid Ahmadi Nasab, Saeed Hesaraki, Nader  Nezafati, “In vitro evaluation of curcumin-loaded chitosan-coated hydroxyapatite nanocarriers as a potential system for effective treatment of cancer”, Journal of Biomaterials Science, Polymer Edition (2021) https://doi.org/10.1080/09205063.2021.1910920.

14. Mohammad Nouri-Felekori, Mehrdad Khakbiz, Nader Nezafati, Javad Mohammadi, Mohamadreza Baghaban Eslaminejad, Nesa Fani, “Characterization and multiscale mo deling of novel calcium phosphate composites containing hydroxyapatite whiskers and gelatin microspheres”, Journal of Alloys and Compounds, 832 (2020) 154938.

15. Saeed Hesaraki, Mohammad Karimi, Nader Nezafati, “The synergistic effects of SrF nanoparticles, YSZ nanoparticles, and poly-ɛ-L-lysin on physicomechanical, ion release, and antibacterial-cellular behavior of the flowable dental composites“, Materials Science & Engineering C, 109, 110592.

16.      Mehdi Shams, Nader Nezafati, Delaram Poormoghadam, Siamak Zavareh, Ali Zamanian, Ali Salimi, “Synthesis and characterization of electrospun bioactive glass nanofibers-reinforced calcium sulfate bone cement and its cell biological response“, Ceramics International, 46(8), 2020.

17. Nader Nezafati, Maryam Farokhi, Mojgan Heydari, Saeed Hesaraki, Navid Ahmadi Nasab, “ In vitro bioactivity and cytocompatablity of an injectable calcium phosphate cement/silanated gelatin microsphere composite bone cement”, Composites Part B, 175 (2019) 107146.

18. Nader Nezafati, Raheleh Faridi-Majidi, Mohammad Pazouki, Saeed Hesaraki, “Synthesis and characterization of a novel freeze‐dried silanated chitosan bone tissue engineering scaffold reinforced with electrospun hydroxyapatite nanofiber”, Polymer International, 68 (8) 2019, 1420-1429.

19. Mohammad Nouri-Felekori, Mehrdad Khakbiz, Nader Nezafati, “Synthesis and characterization of Mg, Zn and Sr-incorporated hydroxyapatite whiskers by hydrothermal method”, Materials Letters 243 (2019) 120–124.

20. Mahtab Rasti, Saeed Hesaraki, Nader Nezafati, “The effects of GPTMS concentration and powder to liquid ratio on the flowability and biodegradation behaviors of 45S5 bioglass/tragacanth bioactive composite pastes”, Journal of Applied Polymer Science, 136 (2019) 47604-47617.

21. Zohre Mousavi Nejad, Bahman Torabinejad, Seyed Mohammad Davachi, Ali Zamanian, Sadaf Saeedi Garakani, Farhood Najafi, Nader Nezafati, “ Synthesis, physicochemical, rheological and in-vitro characterization of double-crosslinked hyaluronic acid hydrogels containing dexamethasone and PLGA/dexamethasone nanoparticles as hybrid systems for specific medical applications”, International Journal of Biological Macromolecules, 126 )2019( 193-208.

22. Mohammad Nouri-Felekori, Mehrdad Khakbiz, Nader Nezafati, Javad Mohammadi, Mohamadreza Baghban Eslaminejad, “Comparative analysis and properties evaluation of gelatin microspheres crosslinked with glutaraldehyde and 3-Glycidoxypropyltrimethoxysilane as drug delivery systems for the antibiotic vancomycin”, International Journal of Pharmaceutics, 557 (2019) 208-220.

23. Kamal Asadipour, Nader Nezafati, Mohammad Sadegh Nourbakhsh, Masoud Hafezi-Ardakani, Saleh Bohlooli, “Characterization and biological properties of a novel synthesized silicon-substituted hydroxyapatite derived from eggshell”, The International Journal of Artificial Organs, 42(2) 2019, 95 –108.

24. Marzie Moraveji, Nader Nezafati, Mohammad Pazouki, Saeed Hesaraki, “Bioorthogonal surface modified α-TCP-based bone filler for enhancement of apatite formation and bioactivity”, Ceramics International,  45 (5) 2019, Pages 5981-5986.

25. Mehdi Shams, Mohammad Karimi, Marzieh Ghollasi, Nader Nezafati, Ali Salimi, “Electrospun poly-l-lactic acid nanofibers decorated with melt-derived S53P4 bioactive glass nanoparticles: The effect of nanoparticles on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro”, Ceramics International, 44 (16) 2018, 20211-20219.

26. Mohammad Karimi, Saeed Hesaraki, Nader Nezafati, “In vitro biodegradability–bioactivity–biocompatibility and antibacterial properties of SrF2 nanoparticles synthesized by one-pot and eco-friendly method based on ternary strontium chloride-choline chloride-water deep eutectic system”, Ceramics International,  44 (11) 2018,  12877-12885.

27. A. Houshyari, M. Heydari, M. Bagheri, N. Nezafati, “Preparation of gelatin nanoparticles by a water-in-oil emulsion method for water-soluble model drug encapsulation”, Materials Today: Proceedings, 5 (7) 2018, 15800–15805.

28. B. Aghabarari, N. Nezafati, M. Roca-Ayats, M.C. Capel-Sánchez, M.J. Lázaro, M.V. Martínez-Huerta, “Effect of molybdophosphoric acid in iron and cobalt graphene/chitosan composites for oxygen reduction reaction”, International Journal of Hydrogen Energy, 42 (46) 2017, 28093-28101.

29. Raheleh Faridi-Majidi, Nader Nezafati, Mohammad Pazouki, Saeed Hesaraki, “The effect of synthesis parameters on morphology and diameter of electrospun hydroxyapatite nanofibers”, Journal of the Australian Ceramic Society, 53 (1) 2017, 225–233.

30. Raheleh Faridi-Majidi, Nader Nezafati, Mohammad Pazouki, Saeed Hesaraki, “Evaluation of morphology and cell behaviour of a novel synthesized electrospun poly(vinyl pyrrolidone)/poly(vinyl alcohol)/hydroxyapatite nanofibers”, Nanomedicine Journal, 4 (2) 2017, 107-114.

31. M. Shamsi, M. Karimi, M. Ghollasi, N. Nezafati, M. Shahrousvand , M. Kamali , A. Salimi , “In vitro proliferation and differentiation of human bone marrow mesenchymal stem cells into osteoblasts on nanocomposite scaffolds based on bioactive glass (64SiO2-31CaO-5P2O5)-polyl-lactic acid nanofibers fabricated by electrospinning method”, Materials Science & Engineering C, 78 (1) 2017, 114-123.

32. Maryam Farokhi, Nader Nezafati , Mojgan Heydari, Saeed Hesaraki, “Use of epoxypropoxy-propyl-trimethoxysilane in the fabrication of bioactive gelatin microspheres using an emulsification method“, Journal of Materials Science, 51, 2016, 9356– 9366.

33. S. Borhan, S.Hesaraki, N. Nezafati, “Synthesis and rheological evaluations of novel injectable sodium alginate/ chitosan-nanostructured hydroxyapatite composite bone pastes“, Journal of the Australian Ceramic Society, 52 (2), 120-127, 2016.

34. S. Pouraghaei, F. Moztarzadeh, N. Nezafati, F. Rahmanian, “Synthesis and Characterization of Silver-containing Sol-gel Derived Bioactive Glass Coating”, Protection of Metals and Physical Chemistry of Surfaces, 2016, 52(2), 285–290.

35. S. Goodarzi, F. Moztarzadeh, N. Nezafati, H. Omidvar, “Titanium dioxide nanotube arrays: A novel approach into periodontal tissue regeneration on the surface of titanium implants”, Advanced Materials Letters, 7(3) 2016, 209-215.

36. Nader Nezafati, Ali Zamanian “Effect of Silane-Coupling Agent Concentration on Morphology and In Vitro Bioactivity of Gelatin-Based Nanofibrous Scaffolds Fabricated by Electrospinning Method”, Journal of Biomaterials and Tissue Engineering, 5 (2015) 78-86.

37. Nader Nezafati, Masoud Hafezi, Ali Zamanian, Mandana Naserirad,” Effect of adding nano-titanium dioxide on the microstrucrure, mechanical properties and in vitro bioactivity of a freeze cast merwinite scaffold”,  Journal of Biotechnology Progress, (2015) 31, 550-556.

38. Mazaher Gholipourmalekabadi, Nader Nezafati, Leila Hajibaki, Masoud Mozafari, Fatollah Moztarzadeh, Saeed Hesaraki, Ali Samadikuchaksaraei, “Detection and qualification of optimum antibacterial and cytotoxic activities of silver-doped bioactive glasses”, IET Nanobiotechnology, 9 (4) 2015, 209-214.

39. Samaneh Saber-Samandari, Saeed Saber-Samandari, Nader Nezafati, Kovan Yahya,“Efficient removal of lead (II) ions and methylene blue from aqueous solution using chitosan/Fe-hydroxyapatite nanocomposite beads”, Journal of Environmental Management 14 (6) 2014, 481-490.

40. Saeed Hesaraki, Nader Nezafati, “In vitro biocompatibility of chitosan/hyaluronic acid-containing calcium phosphate bone cements”, Journal of Bioprocess and Biosystems Engineering (2014) 37, 1507–1516.

41. Masoud Hafezi, Nader Nezafati, Ali Nadernezhad, Mana Yasaei, Ali Zamanian, Sahba Mobini, “Effect of sintering temperature and cooling rate on the morphology, mechanical behavior and apatite-forming ability of a novel nano-structured magnesium calcium silicate scaffold prepared by a freeze casting method”, Journal of Materials Science, 49 (2014) 1297–1305.

42. Nader Nezafati, Fathollah Moztarzadeh, Saeed Hesaraki, Zoha Moztarzadeh, Masoud Mozafari, “Biological response of a recently developed nanocomposite based on calcium phosphate cement and sol-gel derived bioactive glass fibers as substitution of bone tissues”, Ceramics International, 39 (2013) 289–297.

43. Nader Nezafati, Fathollah Moztarzadeh, Saeed Hesaraki,’’ Surface reactivity and in vitro biological evaluation of sol gel derived silver/calcium silicophosphate bioactive glass”, Journal of Biotechnology and Bioprocess Engineering, 17 (4) 2012, 746-754.

44. Nader Nezafati, Saeed Hesaraki, Mostafa Shahrezaee, “Preparation and Physicochemical evaluation of paste-paste calcium hydroxide based dental cement and the effect of replacement of glycol disalicylate by methyl salicylate on its basic properties”, Advanced Composites Letters, 21(3) 2012, 78-83.

45. Maziar Ashuri, Fathollah Moztarzadeh, Nader Nezafati, Ali Ansari Hamedani, Mohammadreza Tahriri, “Development of a composite based on hydroxyapatite and magnesium and zinc containing sol–gel-derived bioactive glass for bone substitute applications”, Materials Science and Engineering: C, 2012, 32, 2330–2339.

46. Nader Nezafati, Fathollah Moztarzadeh, Saeed Hesaraki, Masoud Mozafari “Synergistically reinforcement of a self-setting calcium phosphate cement with bioactive glass fibers”, Ceramics International, 2011, Vol. 37, Issue 3, 927-934.

47. N. Nezafati et al. “Evaluation of a prepared sol-gel bioactive glass fiber-reinforced calcium phosphate cement ”, journal of Ceramic Processing and Research , 2010, Vol. 11, No. 3, 367-371.

48. S. Hesaraki, F.Moztarzadeh, R. Nemati, N. Nezafati, “Preparation and Characterization of Calcium Sulfate-Biomimetic Apatite Nanocomposites for Controlled Release of Antibiotics”, Journal of Biomedical Materials Research: Part B, 2009, 91B: 651–661.

49. S. Hesaraki, F. Moztarzadeh, N. Nezafati, “Evaluation of a bioceramic-based nanocomposite material for controlled delivery of a non-steroidal anti-inflammatory drug”, Journal of Medical Engineering & Physics, 2009, 31, 1205–1213.

1- مجري طرح “ساخت، مشخصه یابی و بررسي خواص بیولوژیکی نسل جدید داربست پایه هیدروکسی اتیل سلولز به کمک شیمی کلیک جهت ترمیم ضایعات غضروفی”،صندوق حمايت از پژوهشگران و فناوران كشور- تاريخ شروع: آبان ماه 1396، تاریخ خاتمه: آبان ماه 1400.

2- مجري طرح ” بررسي فني و اقتصادي سيمانهاي استخواني پايه معدني قابل توليد در كشور و تدوين راهكارهاي لازم براي اخذ تاييديه هاي ملي و بين المللي”، شرکت مشاوران مدیریت توسعه عمید- تاريخ شروع: اسفندماه 1396، تاریخ خاتمه: شهریورماه 1397

3- مجري طرح ” ساخت و بررسي خواص فيزيکي/مکانيکي و زيست سازگاري کامپوزيت سيمان کلسيم فسفاتي /ميکروسفر ژلاتيني حاوي عامل سيلانه کننده “، صندوق حمايت از پژوهشگران و فناوران كشور- تاريخ شروع: آبان ماه 1394، تاریخ خاتمه: اسفندماه 1395.

4- مجري طرح ” ساخت، مشخصه‌يابي و بررسي خواص زيست فعالي/  ضدباكتريايي ايمپلنت‌هاي فلزي پوشش‌داده شده با شيشه‌هاي زيست فعال حاوي نقره تهيه شده به روش سل-ژل به منظور كاربردهاي اورتوپدي”، صندوق حمايت از پژوهشگران و فناوران كشور- تاريخ شروع: مردادماه 1391، تاریخ خاتمه: اسفندماه 1392

5- مجري طرح ” بررسی تاثیر افزودن گلایسیدوکسی پروپیل تری متوکسی سیلان (GPTMS) بر روی خواص و رفتار بیواکتیویته داربست های الکتروریسی شده بر پایه ژلاتین”، پژوهشگاه مواد وانرژی، تاریخ شروع: خردادماه 1392، تاریخ خاتمه: تیرماه 1393

6- همکار طرح ” ساخت و بهبود خواص مکانيکي جايگزين هاي استخواني کلسيم فسفات با استفاده از اکسيدهاي فلزي چقرمه”، پژوهشگاه مواد و انرژی، تاریخ شروع: خردادماه 1394، تاریخ خاتمه: خردادماه 1395

7- همكار طرح ” تدوین دانش فنی، ساخت، مشخصه یابی و ارزیابی بیولوژیکی پیچ های ارتوپدی قابل جذب بر پایه نانو کامپوزیت های پلیمری و سرامیک های زیست فعال “، طرح های صنایع نوین وزارت صنعت، معدن و تجارت – تاريخ تصويب: آذرماه 1396، تاریخ خاتمه: شهریورماه 1397

8- همكار طرح “سنتز نانوذرات SrF2 با کمک حلالهای یوتکتیک عمیق و اثر افزودن آنها بر کامپوزیتهای رزینی دندانی با کاربری فیشرسیلانت”، صندوق حمايت از پژوهشگران و فناوران کشور، تاریخ شروع: اسفندماه 1395، تاریخ خاتمه: مهرماه 1397

اطلاعات آموزشی

اطلاعات تماس
تلفن : 36280040-26-98 داخلی 475
فکس : 36201888-26-98
آدرس : کرج - مشکین دشت - بلوار امام خمینی
ایمیل : n.nezafati@merc.ac.ir
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